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Invitrogen™ TFR2 Recombinant Rabbit Monoclonal Antibody (JG58-34)
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Description
Positive Control: HepG2, human liver tissue, human liver cancer tissue.
This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Specifications
Specifications
| Antigen | TFR2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | JG58-34 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4 |
| Gene | Tfr2 |
| Gene Accession No. | Q9UP52 |
| Gene Alias | HFE3; MGC126368; TfR2; TFRC2; transferrin receptor 2; transferrin receptor protein 2; Trfr2 |
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