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Invitrogen™ TGF beta-1,2,3 Monoclonal Antibody (1D11)
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Catalog No. PIMA523795
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500 μg
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PIMA523795 500 μg
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Catalog No. PIMA523795 Supplier Invitrogen™ Supplier No. MA523795
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Description

Mouse Monoclonal Antibody

This antibody recognizes human TGF-beta 1, TGF-beta 2, and TGF-beta 3. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method. Neutralization: measured by its ability to neutralize TGF beta-1 inhibition of IL-4-dependent proliferation in the HT-2 mouse T cell line. The Neutralization Dose (ND50) is typically 0.25-1.25 μg/mL in the presence of 1 ng/mL Recombinant Human TGF beta-1 and 7.5 ng/mL Recombinant Mouse IL-4.

TGF-beta1, -2, and -3 are a closely related group of proteins (70-80% sequence homology) that are produced by many cell types and function as growth and differentiation factors. The active forms of TGF-beta1, -2, and -3 are disulfide-linked homodimers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGF beta-1,2,3
Applications ELISA, Inhibition Assays, Neutralization, Western Blot
Classification Monoclonal
Clone 1D11
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative; pH 7.4
Gene TGFB1
Gene Accession No. P01137, P04202, P09531, P10600, P16047, P17125, P18341, P21214, P27090, P30371, P61812
Gene Alias CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; tgf beta 1; tgf beta 3; tgf beta1; TGFB; Tgfb1; Tgfb-1; TGFB4; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; TGF-beta4; tissue growth factor-beta4; Transforming growth factor; transforming growth factor beta 1; transforming growth factor beta 4; transforming growth factor beta 4 precursor; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta-1 precursor
Gene Symbols TGFB1, TGFB2, TGFB3
Host Species Mouse
Immunogen Bovine bone-derived TGF-beta 1 and TGF-beta 2.
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100873157, 21803, 21808, 21809, 282089, 396438, 421352, 534069, 538957, 7040, 7042, 7043
Target Species Human, Mouse, Bovine, Chicken
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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Safety and Handling

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