TGIF1 Monoclonal Antibody (OTI1A6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802371

Catalog No. 50-167-9213

Description

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.

Specifications

• Antigen: TGIF1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q15583
• Gene Symbols: TGIF1
• Immunogen: Full length human recombit protein of human TGIF1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1A6
• Conjugate: Unconjugated
• Gene: TGIF1
• Gene Alias: HPE4, TGIF
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7050
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid