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TGIF1 Monoclonal Antibody (OTI1A6), TrueMAB™, OriGene
SDP

Catalog No. 501679213
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50-167-9213 100 μL
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Catalog No. 50-167-9213 Supplier OriGene Supplier No. TA802371
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Description

Mouse Monoclonal Antibody

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.

Specifications

Antigen TGIF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1A6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TGIF1
Gene Accession No. Q15583
Gene Alias HPE4, TGIF
Gene Symbols TGIF1
Host Species Mouse
Immunogen Full length human recombit protein of human TGIF1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7050
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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