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Invitrogen™ TGR5 Polyclonal Antibody
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Catalog No. PIPA523182
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100 μL
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PIPA523182 100 μL
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Catalog No. PIPA523182 Supplier Invitrogen™ Supplier No. PA523182
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Description

Rabbit Polyclonal Antibody

Sequence homology: Bovine (86%).

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGR5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene GPBAR1
Gene Accession No. Q80SS6, Q80T02, Q8TDU6
Gene Alias BG37; C16DUPq36.3; DUP7q36.3; G protein-coupled bile acid receptor 1; G protein-coupled receptor; G protein-coupled receptor TGR5; Gpbar1; GPCR; GPCR HBG37; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; hBG37; Helodermin-preferring VIP receptor; hGPCR19; M-BAR; membrane bile acid receptor; membrane-type receptor for bile acids; PACAP type III receptor; PACAP-R3; PACAP-R-3; pituitary adenylate cyclase-activating polypeptide type III receptor; Tgr5; vasoactive intestinal peptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip2; VIP2R; VIPR2; VIP-R-2; VPAC2; VPAC2 receptor; VPAC2R; VPCAP2R
Gene Symbols GPBAR1
Host Species Rabbit
Immunogen Synthetic peptide from C-terminus of the human TGR5/GPBAR1 protein.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151306, 227289, 338443
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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