Invitrogen™ TGR5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523182

Catalog No. PIPA523182

Description

TGR5 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: TGR5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPBAR1
• Gene Alias: BG37; C16DUPq36.3; DUP7q36.3; G protein-coupled bile acid receptor 1; G protein-coupled receptor; G protein-coupled receptor TGR5; Gpbar1; GPCR; GPCR HBG37; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; hBG37; Helodermin-preferring VIP receptor; hGPCR19; M-BAR; membrane bile acid receptor; membrane-type receptor for bile acids; PACAP type III receptor; PACAP-R3; PACAP-R-3; pituitary adenylate cyclase-activating polypeptide type III receptor; Tgr5; vasoactive intestinal peptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip2; VIP2R; VIPR2; VIP-R-2; VPAC2; VPAC2 receptor; VPAC2R; VPCAP2R
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 151306, 227289, 338443
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q80SS6, Q80T02, Q8TDU6
• Gene Symbols: GPBAR1
• Immunogen: Synthetic peptide from C-terminus of the human TGR5/GPBAR1 protein [UniProt Q8TDU6].
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG