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Eurofins Discoverx Thapsigargin, 1 mg. (92-1148)

Supplier:  Eurofins Discoverx 921148

Encompass

Thapsigargin is a naturally occurring, cell-permeable plant sesquiterpene lactone that non-competitively inhibits the sarco/endoplasmic reticulum calcium ATPase (SERCA, IC50 ~2-80 nM). Effectively increases intracellular calcium levels upon SERCA inhibition, leading to cell activation, increased histamine release from mast cells, and increased cancer cell proliferation. Acts as an anti-inflammatory and induces autophagy in-vivo. Provided as 1 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter,  PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.

Catalog No. 50-199-9679


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