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MAC-MOD Analytical Avantor ACE Excel - Bioanalytical Oligo, 90 A, 1.7 um, 2.1 x 100 mm UHPLC Column
Supplier: MAC-MOD Analytical EXL17151002
There are 2 phases in the Avantor ACE Excel-Bioanalytical line, the ACE Oligo and ACE Glycan. The Oligo stationary phase is chemically modified to withstand an extended pH range. Several impurities can be produced during oligonucleotide synthesis (e.g. failure sequences) which need to be separated from the desired product. Ion-pair RPLC can be employed for the analysis of trityl-off deprotected oligonucleotides. Triethylammonium acetate (TEAA) can be used to ion pair with the negatively charged phosphodiester backbone of the oligonucleotide. The ACE Glycan is a hydrophilic stationary phase which is ideal for glycan analysis due to their highly polar nature. Labelling with a fluorophore such as 2-aminobenzamide (2-AB) allows the released glycans to be analyzed using fluorescence detection. Both columns are available in analytical sizes and in 1.7 micron and 3 micron particle size formats. Note: Guard Columns are available and require guard holder H0011.
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