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Selleck Chemical LLC Cabozantinib malate S4001-50mg
Supplier: Selleck Chemical LLC S400150MG
Cabozantinib malate (XL184) is the malate of Cabozantinib a potent VEGFR2 inhibitor with IC50 of 0 035 nM and also inhibits c-Met Ret (c-Ret) Kit (c-Kit) Flt-1/3/4 Tie2 and AXL with IC50 of 1 3 nM 4 nM 4 6 nM 12 nM/11 3 nM/6 nM 14 3 nM and 7 nM in cell-free assays respectively Cabozantinib malate (XL184) induces apoptosis
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