Thiophene-2-boronic acid, 97%

Description

CAS: 6165-68-0 | C4H5BO2S | 127.95 g/mol

Thiophene-2-boronic acid is a reagent used for Palladium-catalyzed Suzuki-Miyaura cross-couplings, Copper-catalyzed nitration reactions, Chain-growth catalyst transfer polycondensation of conjugated alternating copolymer, Ferric perchlorate-promoted reaction of fullerene to give fullerenyl boronic esters. It is also used in the preparation of Amino pyridine-based inhibitors of mitotic kinase Nek2 with potential antipoliferative effects in cancer tumors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiophene-2-boronic acid is a reagent used for Palladium-catalyzed Suzuki-Miyaura cross-couplings, Copper-catalyzed nitration reactions, Chain-growth catalyst transfer polycondensation of conjugated alternating copolymer, Ferric perchlorate-promoted reaction of fullerene to give fullerenyl boronic esters. It is also used in the preparation of Amino pyridine-based inhibitors of mitotic kinase Nek2 with potential antipoliferative effects in cancer tumors.

Solubility
Soluble in methanol.

Notes
Store in a cool, dry conditions, in well sealed conditions. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6165-68-0
• Molecular Formula: C4H5BO2S
• Molecular Weight (g/mol): 127.95
• MDL Number: MFCD00151850
• InChI Key: ARYHTUPFQTUBBG-UHFFFAOYSA-N
• Synonym: thiophene-2-boronic acid, 2-thiopheneboronic acid, 2-thienylboronic acid, thienylboronic acid, 2-thiopheneboronicacid, thiophen-2-ylboranediol, thiophene2-boronic acid, thiophen-2-yl boronic acid, 2-thiophenylboric acid, boronic acid, thienyl
• PubChem CID: 2733960
• IUPAC Name: thiophen-2-ylboronic acid
• SMILES: OB(O)C1=CC=CS1

• Melting Point: 128°C to 131°C
• Quantity: 1 g
• Beilstein: 112375
• Solubility Information: Soluble in methanol.
• Formula Weight: 127.96
• Percent Purity: 98%
• Chemical Name or Material: Thiophene-2-boronic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	000-000-0
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only