Thioredoxin Reductase 1/TXNRD1/TRXR1 Polyclonal Antibody, Bethyl Laboratories

Catalog No.	Quantity
50-156-8690	20 μL

Catalog No. 50-156-8690 Supplier Bethyl Laboratories, Inc Supplier No. A304791AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Specifications

• Antigen: Thioredoxin Reductase 1/TXNRD1/TRXR1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: TXNRD1
• Gene Accession No.: Q16881
• Gene Alias: trxR1
• Gene Symbols: TXNRD1
• Host Species: Rabbit
• Immunogen: Between 125 and 175
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7296
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG