Invitrogen™ Thrombomodulin Monoclonal Antibody (461714)

Catalog No.	Quantity
PIMA524181	100 μg

Catalog No. PIMA524181 Supplier Invitrogen™ Supplier No. MA524181

Description

Rat Monoclonal Antibody

In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Thrombomodulin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

Specifications

• Antigen: Thrombomodulin
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 461714
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: THBD
• Gene Accession No.: P15306
• Gene Alias: AHUS6; AI385582; BDCA3; BDCA-3; CD141; CD141 antigen; DC141; fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; THBD; THPH12; THRM; thrombomdulin; thrombomodulin; thrombomodulin precursor; TM
• Gene Symbols: THBD
• Host Species: Rat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Thrombomodulin/BDCA-3 Leu17-Ser517.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 21824
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b