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Invitrogen™ Thrombopoietin Monoclonal Antibody (9H10H8D11), Invitrogen™

Catalog No. p-7240480
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Quantity:
50 μL
100 μL
Catalog No. Quantity
PIMA543476 50 μL
PIMA542987 100 μL
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Catalog No. PIMA543476

Supplier: Invitrogen™ MA543476

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Mouse Monoclonal Antibody

Specificity: Human THPO

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thrombopoietin
Applications ELISA
Classification Monoclonal
Clone 9H10H8D11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene THPO
Gene Accession No. P40225
Gene Alias C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX
Gene Symbols THPO
Host Species Mouse
Immunogen Human full-length cell-derived rhTHPO.
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7066
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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