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Thymidine, MP Biomedicals™

Catalog No. MP219475405 Shop All MP Biomedicals, Inc Products
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Description

Used in forming hybrid cell lines where cells are incubated in HAT medium. Thymidine, MP Biomedicals, a cell culture reagent, is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine. It is highly stable and appears

Mainly used in forming hybrid cell lines using HAT (hypoxanthine-aminopterin-thymidine) medium to give rise to monoclonal antibodies. Also used in HT and HAT cocktails for hybridoma fusion, selection and cloning.

Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating respectively dTMP, dTDP or dTTP (deoxythymidine mono-, di-, or triphosphate). The stability of deoxythymidine under standard temperature and pressure (STP) is very high. Thymidine is listed as a chemical teratogen.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-89-5
Molecular Formula C10H14N2O5
Molecular Weight (g/mol) 242.23
InChI Key IQFYYKKMVGJFEH-UHFFFAOYNA-N
Synonym thymidine, deoxythymidine, 2'-deoxythymidine, 5-methyldeoxyuridine, thymidin, beta-thymidine, dthyd, 5-methyl-2'-deoxyuridine, thymine-2-deoxyriboside, thyminedeoxyriboside
PubChem CID 5789
ChEBI CHEBI:17748
IUPAC Name 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
SMILES CC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O

Specifications

Melting Point 185°C to 191°C
Quantity 5 g
Solubility Information Soluble in water, methanol, hot alcohol, hot acetone, hot ethyl acetate pyridine, glacial acetic acid and HCl (20mg/mL, clear, colorless solution); sparingly soluble in hot chloroform.
Optical Rotation 17.5–19.5° (c=1, water)
Formula Weight 242.2
Percent Purity >99.9%
Physical Form Powder

Safety and Handling

Recommended Storage Store at Room Temperature (15–30°C)
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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