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Invitrogen™ Thymidine Phosphorylase Monoclonal Antibody (826722)
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Catalog No. MA561844
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MA561844 100 μg
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Catalog No. MA561844 Supplier Invitrogen™ Supplier No. MA561844
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Description

Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thymidine Phosphorylase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 826722
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene TYMP
Gene Accession No. P19971, Q5FVR2, Q99N42
Gene Alias 2900072D10Rik; ECGF; Ecgf1; endothelial cell growth factor 1 (platelet-derived); gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PDECGF; PD-ECGF; Pdgfec; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; thymidine phosphorylase; TP; TYMP
Gene Symbols TYMP
Host Species Rat
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse PD-ECGF/Thymidine Phosphorylase, Met1-Pro471.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1890, 315219, 72962
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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