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Thymidine Phosphorylase Monoclonal Antibody (P-GF.44C), Invitrogen™

Catalog No. PIMA513542
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500 μL
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PIMA513542 500 μL
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Catalog No. PIMA513542 Supplier Thermo Scientific Supplier No. MA513542
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Description

Mouse Monoclonal Antibody

MA5-13542 targets Thymidine Phosphorylase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples. The MA5-13542 immunogen is recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein.

A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thymidine Phosphorylase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone P-GF.44C
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene TYMP
Gene Accession No. P19971, Q5FVR2, Q99N42
Gene Alias 2900072D10Rik; ECGF; Ecgf1; endothelial cell growth factor 1 (platelet-derived); gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PDECGF; PD-ECGF; Pdgfec; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; thymidine phosphorylase; TP; TYMP
Gene Symbols TYMP
Host Species Mouse
Immunogen Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1890, 315219, 72962
Target Species Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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