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Thymidine Phosphorylase Monoclonal Antibody (P-GF.44C), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Thermo Scientific MA513542
Description
MA5-13542 targets Thymidine Phosphorylase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples. The MA5-13542 immunogen is recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein.
A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Specifications
Thymidine Phosphorylase | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
P19971, Q5FVR2, Q99N42 | |
TYMP | |
Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein | |
500 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG1 |
Immunohistochemistry (Paraffin), Western Blot | |
P-GF.44C | |
Unconjugated | |
TYMP | |
2900072D10Rik; ECGF; Ecgf1; endothelial cell growth factor 1 (platelet-derived); gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PDECGF; PD-ECGF; Pdgfec; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; thymidine phosphorylase; TP; TYMP | |
Mouse | |
Protein G | |
RUO | |
1890, 315219, 72962 | |
4° C | |
Liquid |
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