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Thymidine Phosphorylase Monoclonal Antibody (P-GF.44C), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA513542

Catalog No. PIMA513542


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Description

Description

MA5-13542 targets Thymidine Phosphorylase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples. The MA5-13542 immunogen is recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein.

A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Thymidine Phosphorylase
Monoclonal
0.2 mg/mL
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P19971, Q5FVR2, Q99N42
TYMP
Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein
500 μL
Primary
Human, Mouse, Rat
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
P-GF.44C
Unconjugated
TYMP
2900072D10Rik; ECGF; Ecgf1; endothelial cell growth factor 1 (platelet-derived); gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PDECGF; PD-ECGF; Pdgfec; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; thymidine phosphorylase; TP; TYMP
Mouse
Protein G
RUO
1890, 315219, 72962
4° C
Liquid
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