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Invitrogen™ Thymidine Phosphorylase Monoclonal Antibody (PGF 44C)
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Catalog No. MA146059
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100 μg
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Catalog No. Quantity
MA146059 100 μg
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Catalog No. MA146059 Supplier Invitrogen™ Supplier No. MA146059
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Description

Mouse Monoclonal Antibody

Suggested positive control: HUVEC cells, breast carcinoma.

A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Thymidine Phosphorylase
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone PGF 44C
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TYMP
Gene Accession No. P19971
Gene Alias 2900072D10Rik; ECGF; Ecgf1; endothelial cell growth factor 1 (platelet-derived); gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PDECGF; PD-ECGF; Pdgfec; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; thymidine phosphorylase; TP; TYMP
Gene Symbols TYMP
Host Species Mouse
Immunogen Full length human protein in E. coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1890
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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