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  6. Thyroglobulin Mouse anti-Human, Clone: 4D3C5, Proteintech 

Thyroglobulin Mouse anti-Human, Clone: 4D3C5, Proteintech
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Catalog No. 501736369 Shop All Proteintech Group Inc Products
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50-173-6369 150 μL
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Catalog No. 50-173-6369 Supplier Proteintech Group Inc Supplier No. 602721IG150UL
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Description

Mouse Monoclonal Antibody

Thyroglobulin(Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine.Thyroglobulinis secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Specifications

Antigen Thyroglobulin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 4D3C5
Concentration 1.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TG
Gene Accession No. P01266
Gene Alias AITD3, TG, TGN, thyroglobulin
Gene Symbols TG
Host Species Mouse
Immunogen Thyroglobulin Fusion Protein Ag18070
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7038
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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