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TIAF1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501732829 Shop All Proteintech Group Inc Products
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50-173-2829 150 μL
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Catalog No. 50-173-2829 Supplier Proteintech Group Inc Supplier No. 203281AP150UL
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Description

Rabbit Polyclonal Antibody

TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.

Specifications

Antigen TIAF1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TIAF1
Gene Accession No. O95411
Gene Alias MAJN, MYO18A, MYSPDZ, SPR210, TIAF1
Gene Symbols TIAF1
Host Species Rabbit
Immunogen TIAF1 Fusion Protein Ag14023
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9220
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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