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Tie2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732357 Shop All Proteintech Group Inc Products
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50-173-2357 150 μL
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Catalog No. 50-173-2357 Supplier Proteintech Group Inc Supplier No. 191571AP150UL
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Description

Rabbit Polyclonal Antibody

TIE2, also known as TEK tyrosine kinase, TIE2 gene is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.

Specifications

Antigen Tie2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TEK
Gene Accession No. Q02763, Q02858
Gene Alias Angiopoietin 1 receptor, CD202B, hTIE2, p140 TEK, TEK, TIE 2, Tie2, VMCM, VMCM1
Gene Symbols TEK
Host Species Rabbit
Immunogen Tie2 Fusion Protein Ag13523
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21687, 7010, 89804
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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