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Tie2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 191571AP150UL

Description
TIE2, also known as TEK tyrosine kinase, TIE2 gene is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.Specifications
Tie2 | |
Polyclonal | |
Unconjugated | |
TEK | |
Angiopoietin 1 receptor, CD202B, hTIE2, p140 TEK, TEK, TIE 2, Tie2, VMCM, VMCM1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
21687, 7010, 89804 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.22 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q02763, Q02858 | |
TEK | |
Tie2 Fusion Protein Ag13523 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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