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Tie2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 191571AP150UL

Encompass_Preferred

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Catalog No. 50-173-2357


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Description

Description

TIE2, also known as TEK tyrosine kinase, TIE2 gene is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.
Specifications

Specifications

Tie2
Polyclonal
Unconjugated
TEK
Angiopoietin 1 receptor, CD202B, hTIE2, p140 TEK, TEK, TIE 2, Tie2, VMCM, VMCM1
Rabbit
Antigen Affinity Chromatography
RUO
21687, 7010, 89804
-20°C
Liquid
Immunoprecipitation, Western Blot
0.22 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q02763, Q02858
TEK
Tie2 Fusion Protein Ag13523
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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