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Invitrogen™ TIMP4 Polyclonal Antibody
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Catalog No. PIPA592959
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100 μL
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PIPA592959 100 μL
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Catalog No. PIPA592959 Supplier Invitrogen™ Supplier No. PA592959
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Description

Rabbit Polyclonal Antibody

Positive Samples: HT-29, Mouse heart, Mouse brain, Mouse ovary, Rat heart, Rat brain.

Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIMP4
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.54 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene TIMP4
Gene Accession No. P81556, Q99727, Q9JHB3
Gene Alias Metalloproteinase inhibitor 4; TIMP 4; TIMP metallopeptidase inhibitor 4; TIMP4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4
Gene Symbols TIMP4
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110595, 680130, 7079
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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