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Creative Biomart Tenecteplase; Modified Tissue plasminogen activator (tPA)

Supplier:  Creative Biomart THP0020

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Tissue plasminogen activator (tPA). The product is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 with glutamine, both within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain.

Catalog No. 50-208-4071


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