Invitrogen™ TLR11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141080

Catalog No. 01-676-672

Description

TLR11 Polyclonal Antibody for Western Blot, Flow

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR11 does not respond to known TLR ligands but instead respond specifically to uropathogenic bacteria. TLR11-deficient mice are highly susceptible to infection of the kidneys by uropathogenic bacteria, indicating that TLR11 may play a protective role in preventing infection of internal organs of the urogenital system.

Specifications

• Antigen: TLR11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tlr11
• Gene Alias: Gm1365; Gm287; RGD1564460; RP23-392K10.4; Tlr11; Tlr12; Toll-like receptor 11; Toll-like receptor 12
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 239081, 498491
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q6R5P0
• Gene Symbols: Tlr11
• Immunogen: Synthetic peptide corresponding to residues 911-926 (CEQLKRRLSKAGQERD) of mouse TLR11.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG