Invitrogen™ TLR12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141037

Catalog No. 01-676-644

Description

TLR12 Polyclonal Antibody for Western Blot, Flow

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands.

Specifications

• Antigen: TLR12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tlr12
• Gene Alias: Gm1365; Gm287; MGC129352; MGC129353; RGD1559145; Tlr11; Tlr12; Toll-like receptor 11; Toll-like receptor 12
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 362604, 384059
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: Q6QNU9
• Gene Symbols: Tlr12
• Immunogen: Synthetic peptide corresponding to residues R(743) V W L Q G L R G K G D K G(756) of mouse TLR12.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG