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TLR3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501731777 Shop All Proteintech Group Inc Products
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50-173-1777 150 μL
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Catalog No. 50-173-1777 Supplier Proteintech Group Inc Supplier No. 177661AP150UL
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Description

Rabbit Polyclonal Antibody

TLR3 is involved in Herpes simplex encephalitis 2 (HSE2), a rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infected individuals. HSE is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome. Disease susceptibility is associated with variations affecting the gene represented in this entry. TLR3 mutations predispose otherwise healthy individuals to isolated herpes simplex encephalitis through a mechanism that involves impaired IFNs production and reduced immune defense against viral infection in the central nervous system.

Specifications

Antigen TLR3
Applications Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TLR3
Gene Accession No. O15455, Q99MB1
Gene Alias CD283, TLR3, toll like receptor 3
Gene Symbols Tlr3
Host Species Rabbit
Immunogen TLR3 Fusion Protein Ag12171
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 142980, 364594, 7098
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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