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Invitrogen™ TLR8 Polyclonal Antibody
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Catalog No. PIPA5102413
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PIPA5102413 100 μL
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Catalog No. PIPA5102413 Supplier Invitrogen™ Supplier No. PA5102413
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TLR8.

The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLR8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TLR8
Gene Accession No. P58682, Q9NR97
Gene Alias CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286
Gene Symbols TLR8
Host Species Rabbit
Immunogen A synthesized peptide derived from human TLR8(Accession Q9NR97), corresponding to amino acid residues H986-D1036.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170744, 51311, 684440
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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