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Invitrogen™ TLX2 Polyclonal Antibody
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Catalog No. PIPA559372
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PIPA559372 100 μL
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Catalog No. PIPA559372 Supplier Invitrogen™ Supplier No. PA559372
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Rabbit Polyclonal Antibody

Immunogen sequence: GIDQILSGPE TPGGGLGLGR GGQGHGENGA FSGGYHGASG YGPAGSL Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 74%.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLX2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TLX2
Gene Accession No. O43763
Gene Alias Enteric neuron homeobox protein; Enx; homeo box 11-like 1; homeobox 11-like1; homeobox protein Hox-11L1; Homeobox TLX-2; hox11l; Hox11L.1; Hox11l1; NCX; Ncx1; neural crest homeobox protein; PMUR10F; T cell leukemia homeobox 2; T cell leukemia, homeobox 2; T-cell leukemia associated homeodomain protein; T-cell leukemia associated homeodomain protein Tlx3a; T-cell leukemia homeobox 2; T-cell leukemia homeobox protein 2; T-cell leukemia, homeobox 2; T-cell leukemia, homeobox 3a; Tlx1l1; Tlx1l2; Tlx2; tlx3a; Tlx-3a; tlxA; transcription factor
Gene Symbols TLX2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TLX2. Recombinant protein control fragment (Product #RP-98392).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3196
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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