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Invitrogen™ TM4SF1 Polyclonal Antibody
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Catalog No. PIPA551746
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100 μL
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PIPA551746 100 μL
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Catalog No. PIPA551746 Supplier Invitrogen™ Supplier No. PA551746
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPLCLDSLGQ WNYTFASTEG QYLLDTSTWS ECTEPKHIVE WNVSLFSI Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 77%.

TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TM4SF1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TM4SF1
Gene Accession No. P30408
Gene Alias 12A8 target antigen; H-L6; L6; L6 antigen; M3S1; Membrane component chromosome 3 surface marker 1; membrane component chromosome 3 surface marker 1 homolog; membrane component, chromosome 3, surface marker 1; membrane component, surface marker 1; TAAL6; TM4SF1; transmembrane 4 L six family member 1; transmembrane 4 L6 family member 1; transmembrane 4 superfamily member 1; tumor-associated antigen L6
Gene Symbols TM4SF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TM4SF1. Recombinant protein control fragment (Product #RP-101051).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4071
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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