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Invitrogen™ TMEM189 Polyclonal Antibody
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Catalog No. PIPA563746
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PIPA563746 100 μL
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Catalog No. PIPA563746 Supplier Invitrogen™ Supplier No. PA563746
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Rabbit Polyclonal Antibody

Immunogen sequence: YFCITTGWLN YPLEKIGFWR RLEDLIQGLT GEKPRADDMK WAQKI Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 93%.

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM189
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TMEM189
Gene Accession No. A5PLL7
Gene Alias KUA; TMEM189; transmembrane protein 189
Gene Symbols TMEM189
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TMEM189. Recombinant protein control fragment (Product #RP-100885).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 387521
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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