Invitrogen™ TMEM70 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100188

Catalog No. PIPA5100188

Description

Antibody detects endogenous levels of total TMEM70.

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Specifications

• Antigen: TMEM70
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM70
• Gene Alias: 1110020A09Rik; 2210416J16Rik; MC5DN2; RGD1566224; TMEM70; transmembrane protein 70; transmembrane protein 70, mitochondrial
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 500384, 54968
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9BUB7
• Gene Symbols: TMEM70
• Immunogen: A synthesized peptide derived from human TMEM70(Accession Q9BUB7), corresponding to amino acid residues S35-P85.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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