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Invitrogen™ TMEM70 Polyclonal Antibody
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Catalog No. PIPA5100188
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PIPA5100188 100 μL
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Catalog No. PIPA5100188 Supplier Invitrogen™ Supplier No. PA5100188
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TMEM70.

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM70
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TMEM70
Gene Accession No. Q9BUB7
Gene Alias 1110020A09Rik; 2210416J16Rik; MC5DN2; RGD1566224; TMEM70; transmembrane protein 70; transmembrane protein 70, mitochondrial
Gene Symbols TMEM70
Host Species Rabbit
Immunogen A synthesized peptide derived from human TMEM70(Accession Q9BUB7), corresponding to amino acid residues S35-P85.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 500384, 54968
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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