Invitrogen™ TMPRSS2 Monoclonal Antibody (CL12514)

Catalog No.	Quantity
PIMA546522	100 μL

Catalog No. PIMA546522

Supplier: Invitrogen™ MA546522

Description

Mouse Monoclonal Antibody

Highest antigen sequence indentity to the following orthologs: Rat - 66%, Mouse - 66%.

TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.

Specifications

• Antigen: TMPRSS2
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: CL12514
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TMPRSS2
• Gene Accession No.: O15393
• Gene Alias: D16Ertd61e; EC 3.4.219; epitheliasin; FLJ41954; MGC6821; Plasmic transmembrane protein X; PP9284; PRSS10; Serine protease 10; Tmprss2; TMPS2; Transmembrane protease serine 2; Transmembrane protease serine 2 catalytic chain; Transmembrane protease serine 2 non-catalytic chain; transmembrane protease, serine 2
• Gene Symbols: TMPRSS2
• Host Species: Mouse
• Immunogen: Recombinant protein fragment of Human TMPRSS2 (Product #RP-102679)
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7113
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a