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Invitrogen™ TNFAIP8 Monoclonal Antibody (04)
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Catalog No. PIMA530940
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100 μL
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PIMA530940 100 μL
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Catalog No. PIMA530940 Supplier Invitrogen™ Supplier No. MA530940
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human TNFAIP8.

TNFalpha-IP 8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2 or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF. The induction of TNFalpha-IP 8 by TNF is dependent on the activation of NFkappa B. TNFalpha-IP 8 negatively mediates apoptosis and may also play a role in tumor progression. TNFalpha-IP 8 specifically inhibits caspase-8 activity, which results in the inhibition of BID cleavage and caspase-3 activation during TNF-mediated apoptosis. TNFalpha-IP 8 is expressed at high levels in thymus, bone marrow, lymph node, spleen, thyroid, placenta and various tumor tissues, as well as fetal lung, liver and kidney. TNFalpha-IP 8 is present as three isoforms produced by alternative splicing.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFAIP8
Applications ELISA
Classification Monoclonal
Clone 04
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Tnfaip8
Gene Accession No. O95379
Gene Alias AA987150; E130304C20Rik; ENSMUSG00000073567; GG2-1; Gm10539; head and neck tumor and metastasis-related protein; MDC3.13; MDC-3.13; Nded; NF-kappa-B-inducible DED-containing protein; SCC S2; SCCS2; SCC-S2; Ssc-2; TNF alpha induced protein 8; TNF alpha-induced protein 8; Tnfaip8; TNFalpha IP8; TNFalpha-IP 8; TNFalphaIP8; TNF-induced protein; TNF-induced protein GG2-1; Tumor necrosis factor alpha-induced protein 8; tumor necrosis factor, alpha induced protein 8; tumor necrosis factor, alpha-induced protein 8
Gene Symbols Tnfaip8
Host Species Mouse
Immunogen Recombinant Human TNFAIP8 Protein (Met1-Ile198).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25816
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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