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Invitrogen™ TNFRSF11B Monoclonal Antibody (98A1071)
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Catalog No. PIMA515960
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100 μg
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PIMA515960 100 μg
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Catalog No. PIMA515960 Supplier Invitrogen™ Supplier No. MA515960
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Mouse Monoclonal Antibody

Suggested positive control: Daudi. Immunogen sequence: TQETFPPKYL HYDEETSH.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFRSF11B
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 98A1071
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene TNFRSF11B
Gene Accession No. O00300, O08712, O08727
Gene Alias LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Gene Symbols TNFRSF11B
Host Species Mouse
Immunogen A peptide corresponding to the amino acids 20-37 of human Osteoprotegerin.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100348133, 18383, 25341, 4982
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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