TNFSF9 Mouse anti-Human, Clone: 1B4B1, Proteintech

Catalog No.	Quantity
50-173-6876	150 μL

Catalog No. 50-173-6876 Supplier Proteintech Group Inc Supplier No. 664501IG150UL

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

Specifications

• Antigen: TNFSF9
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 1B4B1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: TNFSF9
• Gene Accession No.: P41273
• Gene Alias: 4 1BB L, 4 1BB ligand, 4 1BBL, CD137L, TNFSF9
• Gene Symbols: TNFSF9
• Host Species: Mouse
• Immunogen: TNFSF9 Fusion Protein Ag12768
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8744
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1