TNNT2 Monoclonal Antibody (OTI7D2), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-1798	100 μL

Catalog No. 50-168-1798 Supplier OriGene Supplier No. TA807841

Description

Mouse Monoclonal Antibody

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.

Specifications

• Antigen: TNNT2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI7D2
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TNNT2
• Gene Accession No.: P45379
• Gene Alias: CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
• Gene Symbols: TNNT2
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TNNT2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7139
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b