TNNT2 Monoclonal Antibody (OTI7D2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA807841

Catalog No. 50-168-1798

Description

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.

Specifications

• Antigen: TNNT2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TNNT2
• Gene Alias: CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7139
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI7D2
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P45379
• Gene Symbols: TNNT2
• Immunogen: Full length human recombit protein of human TNNT2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b