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TNP, Tocris Bioscience™

Catalog No. 394610
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Catalog No. Quantity
39-461-0 10 mg
39-465-0 50 mg
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Catalog No. 39-461-0 Supplier R&D Systems Supplier No. 3946/10
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Description

Inhibitor of IP6K; also inhibits IP3K

Reversible inositol hexakisphosphate kinase (IP6K) inhibitor (IC50 = 0.47 μM for inhibition of InsP7 formation). Also inhibits inositol 1,4,5-trisphosphate 3-kinase (IP3K) (IC50 = 10.2 μM). Binds to the ATP binding site of IP3K (Ki = 4.3 μM).

Chemical Identifiers

CAS 519178-28-0
Molecular Formula C20H16F3N7O2
Molecular Weight (g/mol) 443.39
InChI Key DDSBPUYZPWNNGH-UHFFFAOYSA-N
Synonym ip3k inhibitor, tnp, inositol-1,4,5-trisphosphate 3-kinase inhibitor, n2-m-trifluorobenzyl , n6-p-nitrobenzyl purine, n6-4-nitrophenyl methyl-n2-3-trifluoromethyl phenyl methyl-9h-purine-2,6-diamine, purine, 5, tnp hplc, n2-3-trifluoromethyl benzyl-n6-4-nitrobenzyl-9h-purine-2,6-diamine, n∼6∼-4-nitrophenyl methyl-n∼2∼-3-trifluoromethyl phenyl methyl-7h-purine-2,6-diamine
PubChem CID 16760513
IUPAC Name 6-N-[(4-nitrophenyl)methyl]-2-N-[[3-(trifluoromethyl)phenyl]methyl]-7H-purine-2,6-diamine
SMILES C1=CC(=CC(=C1)C(F)(F)F)CNC2=NC3=C(C(=N2)NCC4=CC=C(C=C4)[N+](=O)[O-])NC=N3

Specifications

Quantity 10 mg
Formula Weight 443.38
Percent Purity >97%
Chemical Name or Material TNP

Safety and Handling

Recommended Storage Store at +4°C
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