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Tocris Bioscience™ Colivelin
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Catalog No. 3945500U
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500 μg
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39-455-00U 500 μg
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Catalog No. 39-455-00U Supplier Tocris Bioscience™ Supplier No. 3945/500U
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STAT3 activator; also protects against β-amyloid neurotoxicity

Colivelin is a neuroprotective peptide and activator of STAT3. Protects neurons against the neurotoxic effects of amyloid β-peptide (1-43) at a concentration of 100 fM in vitro. Suppresses neuronal death by activating STAT3 in vitro; upregulates cholinergic transmission and ameliorates memory impairment in Alzheimer's disease (AD) models. Also prevents alcohol-induced apoptosis in a fetal mouse model. Brain penetrant.

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