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Tocris Bioscience™ Compstatin Available on GSA/VA Contract for Federal Government customers only.

C3-binding protein, inhibits complement activation

Manufacturer:  Tocris Bioscience™ 2585/1

Catalog No. 25-851


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Description

Description

Complement inhibitor; binds C3 inhibiting proteolytic cleavage by C3 convertase (IC 50 = 28 µM) and activation of classical and alternative complement pathways (IC 50 values are 63 and 12 µM respectively). Prolongs graft survival and reduces hyperacute rejection of ex vivo pig kidneys perfused with human blood and inhibits in vivo heparin/protamine-induced complement activation in baboons. Control Peptide also available.

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Specifications

Specifications

1mg
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