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Tocris Bioscience™ Cyclotraxin B Available on GSA/VA Contract for Federal Government customers only.

TrkB receptor antagonist

Manufacturer:  Tocris Bioscience™ 5062/1

Catalog No. 50621


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Description

Description

Antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.

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Specifications

Specifications

1mg
SDS
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