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Tocris Bioscience™ Cyclotraxin B
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Catalog No. 50621
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

TrkB receptor antagonist

Cyclotraxin B is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.

Specifications

Quantity 1 mg
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