Tocris Bioscience Gap 26
Gap junction blocker; inhibits smooth muscle contraction and IP3-mediated ATP release
Manufacturer: Tocris Bioscience 1950/1
DescriptionPeptide, corresponding to residues 63 - 75 of connexin 43, which is a gap junction blocker. Attenuates rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). Also inhibits IP3-induced ATP release, without inhibiting gap junctional coupling in endothelial cells.
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