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Tocris Bioscience™ HS 024 Available on GSA/VA Contract for Federal Government customers only.

Highly potent MC4 receptor antagonist

Manufacturer:  Tocris Bioscience™ 1832/1

Catalog No. 18-321


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Description

Description

Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.

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