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Tocris Bioscience™ Jingzhaotoxin III
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Catalog No. 4913100U
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100 μg
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Catalog No. Quantity
49-131-00U 100 μg
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Catalog No. 49-131-00U Supplier Tocris Bioscience™ Supplier No. 4913/100U
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Description

Selective NaV1.5 channel blocker

Jingzhaotoxin III is a selective blocker of NaV1.5 channels (IC50 = 348 nM); displays no effect on other isoforms, including NaV1.2, NaV1.4, NaV1.6 and NaV1.7. Thought to inhibit sodium channel activation by binding to the NaV1.5 S3-S4 linker of domain II. Selectively inhibits the activation of cardiac sodium channels, but has no effect on sodium channels in dorsal root ganglion neurons.

Specifications

Purity 0.95
Quantity 100 μg
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