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Tocris Bioscience™ K 41498
GREENER_CHOICE

Catalog No. 20701
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly selective and potent CRF2 antagonist

K 41498 is a potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. In rats in vivo, blocks urocortin-induced hypotension following systemic administration.

Specifications

Purity 95%
Content And Storage Store at -20°C
Quantity 1 mg
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