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Tocris Bioscience™ ShK-Dap22

Catalog No. 3220100U
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100 μg
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Catalog No. Quantity
32-20100U 100 μg
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Catalog No. 32-20100U Supplier Tocris Bioscience™ Supplier No. 3220/100U
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Description

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

ShK-Dap22 is an extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4). Suppresses T cell activation in vitro (IC50 < 500 pM).

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Quantity 100 μg
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