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Tocris Bioscience™ SHU 9119
GREENER_CHOICE

Catalog No. 34201
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

MC3 and MC4 antagonist; MC5 partial agonist

SHU 9119 is a potent melanocortin MC3 and MC4 receptor antagonist (IC50 values are 0.23 and 0.06 nM respectively) and MC5 partial agonist (EC50 = 0.12 nM). Upregulates expression of genes promoting lipogenesis and triglyceride storage (SCD1, LPL, ACCα and FAS), increases triglyceride synthesis and promotes insulin resistance. Increases food intake, body weight and fat mass when administered centrally in vivo.

Specifications

Purity 0.95
Quantity 1 mg
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