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Tocris Bioscience™ SHU 9119
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Catalog No. 34201
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34-201 1 mg
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Catalog No. 34-201 Supplier Tocris Bioscience™ Supplier No. 3420/1
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Description

MC3 and MC4 antagonist; MC5 partial agonist

SHU 9119 is a potent melanocortin MC3 and MC4 receptor antagonist (IC50 values are 0.23 and 0.06 nM respectively) and MC5 partial agonist (EC50 = 0.12 nM). Upregulates expression of genes promoting lipogenesis and triglyceride storage (SCD1, LPL, ACCα and FAS), increases triglyceride synthesis and promotes insulin resistance. Increases food intake, body weight and fat mass when administered centrally in vivo.

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Purity 0.95
Quantity 1 mg
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