TOMM22 Mouse anti-Human, Clone: 1C2B11, Proteintech

Catalog No.	Quantity
50-173-6981	150 μL

Catalog No. 50-173-6981 Supplier Proteintech Group Inc Supplier No. 665621IG150UL

Description

Mouse Monoclonal Antibody

66562-1-Ig recognizes a22 kDa protein that is larger than the calculated MW of 15 kDa.

Tom22 has a negatively charged N-terminal region exposed to the cytosol, a putative transmembrane region, and a C-terminal intermembrane space region with little negative charge. The following functions can be assigned to the three domains of Tom22: the cytosolic N-terminal domain plays a dual role, specifically important for presequence binding; the intermembrane space domain provides a trans binding site for presequences, and the single membrane anchor of Tom22 is crucial for the integrity of the GIP (general import gene) complex. The TOM complex of mammalian mitochondria resembles the fungal Tom complex, but is distinct from the plant TOM system. Thus, while unique components of the mammalian mitochondrial import system have been identified (e. g. TOM34 and metaxin), Tom22, and Tom37 have not been identified in plant mitochondria.

Specifications

• Antigen: TOMM22
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1C2B11
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: TOMM22
• Gene Accession No.: Q9NS69
• Gene Alias: 1C9 2, hTom22, MST065, MSTP065, TOM22, TOMM22
• Gene Symbols: TOMM22
• Host Species: Mouse
• Immunogen: TOMM22 Fusion Protein Ag1797
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 56993
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a