Invitrogen™ Tomosyn Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565579

Catalog No. PIPA565579

Description

Immunogen sequence: SAHVIIYRFSK QEVITEVIPM LEVRLLYEIN DVETPEGEQP PPLPTPVGGS NPQPIPPQSH PSTSSSSSDG LRDN Highest antigen sequence identity to the following orthologs - mouse 95%, rat 93%.

Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Tomosyn
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STXBP5
• Gene Alias: 0710001E20Rik; 4930565N16Rik; AW742610; FLJ30922; Kiaa4253; L Nbla04300; Lethal(2) giant larvae protein homolog 3; LGL3; LLGL3; MGC141942; MGC141968; mKIAA1006; Nbla04300; putative protein product of Nbla04300; RP11-361F15.4; STXB5; Stxbp5; syntaxin binding protein 5; syntaxin binding protein 5 (tomosyn); syntaxin-binding protein 5; tomosyn; tomosyn 1; tomosyn-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 134957
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5T5C0
• Gene Symbols: STXBP5
• Immunogen: Recombinant Human Tomosyn. Recombinant protein control fragment (Product #RP-106244).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov