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TORC1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501558397
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Quantity:
100 μL
Catalog No. Quantity
50-155-8397 100 μL
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Catalog No. 50-155-8397

Supplier: Bethyl Laboratories, Inc A300768A

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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 ′Ser-133′ phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintece at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.

Specifications

Antigen TORC1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene CRTC1
Gene Accession No. Q6UUV9
Gene Alias CREB-regulated transcription coactivator 1; TORC-1; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; transducer of regulated cAMP response element-binding protein 1
Gene Symbols CRTC1
Host Species Rabbit
Immunogen Between 25 and 75
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23373
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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