Invitrogen™ TPH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1778

Catalog No. 01-670-150

Description

PA1-778 detects TPH2 in human, mouse, rat, rabbit and non-human primate samples. PA1-778 has been successfully used in immunocytochemistry, immunoprecipitation, and Western blot procedures. By Western blot PA1-778 detects a 56 kDa protein representing TPH2. The PA1-778 immunogen is a synthetic peptide corresponding to the N-terminal region of TPH2.

Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Specifications

• Antigen: TPH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tph2
• Gene Alias: ADHD7; AU043594; MGC119994; Neuronal tryptophan hydroxylase; NTPH; Tph2; TPRH; TRPH; Tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; tryptophan hydroxylase 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100344397, 121278, 216343, 317675
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.1% sodium azide
• Gene Accession No.: Q8CGU9, Q8CGV2, Q8IWU9
• Gene Symbols: Tph2
• Immunogen: Synthetic peptide corresponding to the N-terminal region of TPH2: R(15) R G L S L D S A V P E D H Q L (30).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Monkey
• Product Type: Antibody
• Isotype: IgG