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Invitrogen™ TPT1 Polyclonal Antibody
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Catalog No. PIPA534503
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100 μg
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Catalog No. Quantity
PIPA534503 100 μg
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Catalog No. PIPA534503 Supplier Invitrogen™ Supplier No. PA534503
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-34503 can be used with blocking peptide PEP-1546.

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TPT1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TPT1
Gene Accession No. P13693, P63028, P63029
Gene Alias 21 kDa polypeptide; 21 kDa polypeptide under translational control; fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1
Gene Symbols TPT1
Host Species Rabbit
Immunogen A 19 amino acid peptide near the center of human TPT1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116646, 22070, 7178
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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