TRA-1-81 Antigen Mouse anti-Human, PE, Clone: TRA-1-81, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB560885	BD Biosciences 560885	25 Tests
BDB560161	BD Biosciences 560161	100 Tests

Description

The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.

Specifications

• Antigen: TRA-1-81 Antigen
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Target Species: Human
• Immunogen: Human Embryonal Carcinoma Cell Line
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: TRA-1-81
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cell Biology
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Isotype: IgM κ
• Purification Method: Affinity Purified

For Research Use Only.