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TRAF1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735474 Shop All Proteintech Group Inc Products
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50-173-5474 150 μL
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Catalog No. 50-173-5474 Supplier Proteintech Group Inc Supplier No. 268451AP150UL
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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

Antigen TRAF1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TRAF1
Gene Accession No. Q13077
Gene Alias EBI6, TRAF1
Gene Symbols TRAF1
Host Species Rabbit
Immunogen TRAF1 Fusion Protein Ag25397
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7185
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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